Dr. Karthik Raghuram

Profile Brief:

Dr. Karthik Raghuram is a highly accomplished Interventional Cardiologist with over 4 years of experience in advanced cardiovascular care, including coronary and structural interventions. A gold medalist and academic topper throughout his medical education, Dr. Karthik holds an MBBS from Bangalore Medical College, an MD from JIPMER, and a DM in Cardiology from the prestigious Sree Chitra Tirunal Institute.

He currently serves as a Consultant Cardiologist at Kauvery Hospital, Bangalore, and has previously held key roles at Jayadeva Institute and Manipal Hospital, Jayanagar. Dr. Karthik has co-investigated several global clinical trials (including LIBREXIA and ATHENA) and authored multiple publications in peer-reviewed journals. His clinical interests include speckle tracking and 3D echocardiography, and he has presented at numerous national and international conferences. Dr. Karthik combines clinical excellence with academic rigor, making him one of the promising young cardiologists in India today.

Education:

• M.B.B.S - Bangalore Medical College and Research Institute (BMCRI), Bangalore
• M.D. General Medicine JIPMER, Pondicherry, India
• DM Cardiology - Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala

Past Experience:

• Assistant Professor, Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences and Research, Bangalore, Karnataka, India (2021-2025)
• Consultant Cardiologist, Manipal Hospital Jayanagar, Bangalore, Karnataka, India (2022- 2025)
• Consultant Cardiologist, Deepak Hospital Jayanagar, Bangalore, Karnataka, India (2021-present)

Expertise:

• Interventional Cardiology- Coronary and Structural Interventions
• Intracoronary imaging
  - IVUS
  - OCT
• Coronary physiology assessment
• Cardiac hemodynamic assessment
• Speckle Tracking Echocardiography and 3D Echocardiography

Accomplishments and Awards:

• Best Outgoing Student and Pope Gold Medal- 10^th Standard (Bishop Cottons, Bangalore)
• GOLD MEDAL (Institute Medal, Bangalore Medical College and research Institute)- Highest Marks in MBBS Phase I
• National entrance cum eligibility post graduation (NEET PG)
  - All India Rank- 4
  - State rank (Karnataka)- 1

• 1^st Place in EP Quiz- Kerala Heart Rhythm Society Conference 2019, Thiruvananthapuram
• 1^st place Cardiology Quiz- Trivandrum Medical College, Thiruvananthapuram, Jan 2020
• Best paper presentation- CSI HFCON, Kochi, 2019,
• Best poster presentation CSI Annual conference (Virtual)- Dec 2020
  - Karthik R, Krishna Kumar Mohanan Nair, Narayanan Namboodiri, Mukund A Prabhu, Ajitkumar Valaparambil- “Story of a tired Heart”- A Case of Tachycardiomyopathy Managed by Successful Ablation of Right Ventricular Outflow Tract Mid Septum Premature Ventricular Complexes.

Research & Publications:

COMPLETED RESEARCH PROJECTS

1. Arrhythmias in Post-Surgical Tetralogy of Fallot
2. Clinical Profile and outcomes of Semi-permanent pacing in a Tertiary Care Institute in Southern India
3. Clinical Profile and outcomes of Stress Cardiomyopathy in a Tertiary Care Institute in Southern India
4. Factors Associated with Normal Flow (TIMI 3) After Thrombolysis With Streptokinase in ST- Elevation Myocardial Infarction: A Prospective Observational Study
5. Study Of Atrial Arrhythmias After Surgical Or Device Closure Of Atrial Septal Defect

Current Research Projects:

1. A Phase 3 Randomised, Double Blind, Double Dummy, Parallel Group, Active-Controlled Study to Evaluate the Efficacy and Safety of Milvexian, an Oral Factor XIa Inhibitor versus Apixaban in Participants with Atrial Fibrillation (LIBREXIA AF trial)- Co investigator
2. Effects of Ziltivekimab versus placebo on morbidity and mortality in patients with heart failure with mildly reduced or preserved ejection fraction and systemic inflammation (HERMES trial)- Co investigator
3. A Phase 3, Randomized, Double-blind, Placebo-controlled, Event-driven Study to Demonstrate the Efficacy and Safety of Milvexian, an Oral Factor XIa Inhibitor, After a Recent Acute Coronary Syndrome (LIBREXIA ACS trial)- Co investigator
4. Effects of ziltivekimab versus placebo on heart failure symptoms and physical function in patients with heart failure with mildly reduced or preserved ejection fraction and systemic inflammation (ATHENA trial)- Co investigator
5. Effectiveness of Yoga based Cardiac Rehabilitation (Yoga-Care) in Heart Failure: A Randomised Clinical Trial- Co investigator

Publications:

1. Raghuram K, Sasidharan B, Agarwal A, Gangil N. TCTAP C-112 Trans Catheter Aortic Valve Replacement in the Presence of Starr-Edward Prosthesis in Mitral Position Using Balloon Expandable Prosthesis - Technical Challenges. J Am Coll Cardiol. 2021 Apr;77(14):S245–7.
2. Raghuram K, Deepanjali S, Ananthakrishna Pillai A. Factors Associated With Normal Flow (TIMI 3) After Thrombolysis With Streptokinase in ST-Elevation Myocardial Infarction: A Prospective Observational Study. Cureus. 2021 Jan 18;13(1):e12758
3. Abhishekh HA, Raghuram K, Shivakumar S, Balaji AL. Prevalence of depression in community dwelling elderly: Study from rural population of India. J Neurosci Rural Pract. 2013 Aug;4(Suppl 1):S138.
4. Raghuram K, Mohanan Nair KK, Namboodiri N, Das D, Valaparambil A. Management of a complicated ‘pacemaker pocket’ site infection. Natl Med J India 2021;34:84-85
5. Raghuram K, Nair KKM, Namboodiri N, Abhilash SP, Valaparambil AK. Clinical profile and outcomes of semi-permanent pacing in a tertiary care institute in southern India. Indian Pacing Electrophysiol J. 2023 Jan;23(1):17–20.
6. Mohankumar N, Namboodiri N, Nair KKM, Raghuram K, Valaparambil A, Mahadevan KK. Study of atrial arrhythmias after surgical or device closure of atrial septal defect. Natl Med J India. 2022;35(5):271–5.
7. Raghuram K, Nair KKM, Namboodiri N, Valaparambil A. Tachycardiomyopathy managed by successful ablation of right ventricular outflow tract premature ventricular complexes. Natl Med J India. 2022 Jan 29;34(4):211–3.
8. Raghuram K, Gopalakrishnan A, Nair KKM, Namboodiri N, Valaparambil A. Left ventricular apical aneurysm in Takayasu arteritis and chronic active Epstein-Barr virus infection. Egypt Heart J EHJ Off Bull Egypt Soc Cardiol. 2024 Aug 9;76(1):100.

Scientific Abstracts(Poster/Oral Presentation):

1. Abhishekh HA, Raghuram K, Shivakumar S, Balaji AL. Prevalence of depression in community dwelling elderly: Study from rural population of India. – Poster presentation in Aging in America Conference, Chicago, USA- March 2013
2. Karthik Raghuram, Bijulal Sasidharan, Ankur Agarwal, Nishant Gangil - Trans Catheter Aortic Valve Replacement in the Presence Of Starr-Edward Prosthesis In Mitral Position Using Balloon Expandable Prosthesis- Technical Challenges- TCT Asia Pacific (TCTAP) conference Virtual April 2021
3. Karthik Raghuram, Krishna Kumar Mohanan Nair, Narayanan Namboodiri, Ajitkumar Valaparambi. When the going gets tough!- Management of a complicated case of pocket site infection Kerala Heart Rhythm Society Aug 2020
4. Karthik Raghuram, Krishna Kumar Mohanan Nair, Narayanan Namboodiri, Mukund A Prabhu, Ajitkumar Valaparambil- “Story of a tired Heart”- A Case of Tachycardiomyopathy Managed by Successful Ablation of Right Ventricular Outflow Tract Mid Septum Premature Ventricular Complexes CSI Heart Failure Conference, Kochi 2019
5. Karthik Raghuram, Narayanan Namboodiri, Ajit Kumar Valaparambil, , Sreevilasam Pushpangadhan Abhilash- Clinical Profile and Outcomes of Semi-Permanent pacing in a Tertiary Care Institute in Southern India- Indian Heart Rhythm Society Annual Conference- October 2020
6. Karthik Raghuram- Management of Aortopathy with severe aortic regurgitation in a child with Loeys-Dietz syndrome- ICC Annual Conference, Kochi 2019
7. Karthik Raghuram, Sanjay G , Ajitkumar Valaparambil , Harikrishnan S- Clinical Profile and Outcomes of Stress Cardiomyopathy in a Tertiary Care Institute in Southern India – Heart failure Association of India(HFAI)- Annual Conference Jan 2020
8. Karthik Raghuram, Krishna Kumar Mohanan Nair, Narayanan Namboodiri, Mukund A Prabhu, Ajitkumar Valaparambil- “Story of a tired Heart”- A Case of Tachycardiomyopathy Managed by Successful Ablation of Right Ventricular Outflow Tract Mid Septum Premature Ventricular Complexes Poster Presentation APHRS (Virtual) October 2020
9. Karthik Raghuram- Oral Presentation- Re-Emergence of Beta Blockers in Hypertension Management- IDF PRIMER INTERNATIONAL DIABETES SUMMIT 2024