Importance of Kidney Transplant treating renal disease
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The importance of Kidney Transplant in treating End Stage renal disease

Home > Blog > The importance of Kidney Transplant in treating End Stage renal disease

The importance of Kidney Transplant in treating End Stage renal disease

Thursday, 21 December, 2023

The kidneys are remarkable organs with a crucial role in maintaining the body's internal balance. These bean-shaped powerhouses, located just below the ribcage on either side of the spine, perform a multitude of functions that are essential for our overall health. Their primary task is to filter waste products and excess fluids from the blood, converting them into urine for elimination. Additionally, kidneys help regulate blood pressure, electrolyte levels, and red blood cell production, ensuring the body's stability. Beyond their physiological functions, kidneys play a vital role in detoxification, making them indispensable for our well-being. Taking care of these incredible organs through a healthy lifestyle and regular check-ups is pivotal to maintaining optimal kidney function and overall health.

Chronic Kidney Disease

In chronic kidney disease, also known as CKD, there is an accumulation of toxic waste products in the body resulting in permanent damage to the kidneys. While the kidneys may work well enough for a person to live, the condition is irreversible and often worsens over time until the kidneys fail known as end-stage renal disease (ESRD) .

Diabetes and high blood pressure are the leading causes of chronic kidney disease and kidney failure. The disease can also be caused by a physical injury to the kidney or by other diseases. When the kidneys are damaged, they do not effectively remove wastes and extra water from the blood.

End Stage Renal Disease (Kidney Failure)

Chronic kidney disease may eventually result in complete kidney failure.Based on one’s kidney function CKD is divided into 5 stages i.e.

  • Stage 1 eGFR 90 or higher and kidney damage
  • Stage 2 eGFR 60-89 and kidney damage
  • Stage 3 Mild to moderate loss of kidney function
  • Stage 4 Severe loss of kidney function
  • Stage 5 This is the last stage of CKD (Stage 5), also referred to as end-stage renal disease (ESRD). When the kidneys totally fail, either dialysis or a kidney transplant is required.

Renal Replacement Therapy is an option of renal therapy include Hemodialysis, Hemofiltration, and Renal Transplantation. Dialysis replaces partial function and short term mechanism.

Common Causes of End-Stage Renal Disease

  • Diabetes mellitus
  • High blood pressure
  • Glomerulonephritis
  • Polycystic Kidney Disease
  • Severe anatomical problems of the urinary tract

Kidney Transplant

Kidney transplant plays a crucial role in treating end-stage kidney disease(ESKD) and offers several significant advantages over other forms of treatment, such as dialysis. Here are the key reasons why kidney transplant is important in the management of ESKD:

  • Improved Quality of Life: A successful kidney transplant allows individuals to regain a near-normal quality of life. They no longer need frequent dialysis sessions and can return to work, travel, and engage in daily activities more freely.
  • Long-Term Survival: Kidney transplantation generally provides better long-term survival rates compared to long-term dialysis. It significantly extends life expectancy for individuals with ESKD.
  • Reduced Health Risks: Prolonged dialysis can lead to complications and increased risks of infections, cardiovascular issues, and other health problems. Transplantation reduces these risks.
  • Freedom from Dialysis: Dialysis is a time-consuming and physically taxing procedure. Kidney transplant recipients can enjoy freedom from these frequent and often tiring treatments.
  • Improved Nutrition: Kidney transplant often leads to improved appetite and better nutrition, as dietary restrictions are less stringent compared to dialysis.
  • Enhanced Psychological Well-Being: Patients often experience improved mental health and reduced stress after a successful transplant, as they are no longer tied to a dialysis schedule.
  • Cost-Effective: While the initial transplant procedure and post-operative care can be expensive, in the long run, transplantation is often more cost-effective than long-term dialysis, which requires ongoing expenses.
  • Opportunity for Normal Growth (for children): Children who receive a kidney transplant can grow and develop more normally, which may not be the case with long-term dialysis.
  • Potential for Multiple Transplants: Some individuals may need more than one kidney transplant in their lifetime, which is possible in many cases. It's important to note that while kidney transplantation offers numerous benefits, it also comes with its own set of challenges, including the need for immunosuppressive medications to prevent rejection, the requirement for a compatible donor, and the risk of surgical complications. However, for many individuals with ESKD, kidney transplantation remains the most effective and life-enhancing treatment option.


Kidney transplantation is a medical marvel that has transformed the lives of countless individuals facing the dire consequences of End-Stage Renal Disease. It offers not only the promise of prolonged life but also a return to a higher quality of life. While challenges remain, ongoing efforts to increase organ availability and advancements in transplant techniques continue to improve outcomes.

At Kauvery Hospital we offer world-class medical expertise, cutting-edge technology, and patient-centric approach. Our experienced Nephrologist in Bangalore has more than 37+ year of experience. Dr. Krishna Kishore and Dr. Ram Mohan Bhat, are Best Kidney Specialist in Bangalore. They have helped many people get a second chance at life through kidney transplantation. Providing personalized treatment plans ensuring the best possible outcomes. Trust us for compassionate care and excellence in Nephrology treatment.

Authored By: Dr. Krishna Kishore C
Director - Institute of Nephrology
Department - Nephrology
Qualification - MBBS MD DM


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